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Computes the AST/ALT ratio (De Ritis ratio) = AST / ALT, a standard published liver-enzyme index (De Ritis F, et al. 1957). Commonly cited reference framing: a ratio below 1 is commonly associated with viral hepatitis or non-alcoholic fatty liver disease, while a ratio above 2 is commonly associated with alcoholic liver disease. Pure arithmetic on given lab values. For general reference and educational purposes only — not a medical diagnosis. Consult a doctor for actual interpretation of liver function tests.
How it works
Enter AST and ALT values (U/L) from a liver function panel. The tool divides AST by ALT.
- Enter aST (U/L).
- Enter aLT (U/L).
- Click Calculate to see your results.
Examples
AST 40, ALT 40
Ratio = 40/40 = 1.0.
AST 80, ALT 30
Ratio = 80/30 = 2.67 — commonly cited as associated with alcoholic liver disease when markedly elevated.
Who should use it
- Reviewing a liver function panel.
- Liver disease pattern education.
Industry applications
- Hepatology reference
- Clinical education
Advantages
- Simple, standard formula.
- Long-established reference interpretation.
Limitations
- Reference cutoffs vary somewhat by source.
- Does not replace clinical interpretation of the full liver panel.
Common mistakes to avoid
- Interpreting the ratio without considering the absolute AST and ALT values (a ratio can look "normal" even when both enzymes are markedly elevated).
Best practices
- Review the ratio together with absolute AST/ALT levels and other liver panel values.
Tips
- The De Ritis ratio is typically interpreted alongside GGT, bilirubin, and clinical history, not as a standalone value.